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Illustration of the urethra, the tube that carries urine from the bladder to the outside of the body

Primary urethral cancer

Primary urethral cancer is a rare cancer that starts in the lining of the urethra, the tube that carries urine from your bladder out of your body. The disease is more common in patients older than 75. Learn about symptoms and treatment options to better understand this condition.

Which applies to you?

This chapter contains general information about primary urethral cancer. It is not a substitute for professional medical advice or treatment. Always consult your doctor or healthcare provider for guidance on your individual medical situation.

Last updated: April 2026

Reviewed by (2026 update): 

  • Prof. Dr. Antoine Van Der Heijden (EAU Guidelines Panel on Muscle-invasive and Metastatic Bladder Cancer)
  • Prof. Dr. Yann Neuzillet (EAU Guidelines Panel on Muscle-invasive and Metastatic Bladder Cancer)