Clinical trials for bladder cancer

If your cancer has spread or if it keeps coming, especially if your previous chemotherapy didn’t work, you can think about joining a clinical trial. These trials are available for both patients who haven’t had chemotherapy yet and those who have already been treated. 

A clinical trial is a study that tests new treatments, medicines, or medical devices to see if they work well and are safe. It helps doctors find better ways to treat diseases. In a clinical trial, patients might receive the new treatment being tested or the standard treatment to compare the results. The goal is to improve patient care.

This chapter contains general information about clinical trials for bladder cancer. It is not a substitute for professional medical advice or treatment. Always consult your doctor or healthcare provider for guidance on your individual medical situation.

Last updated: April 2026

Reviewed by (2026 update): 

• Dr. Laura Mertens (EAU Guidelines Panel on Muscle-invasive and Metastatic Bladder Cancer)
• Prof. Dr. Antoine Van Der Heijden (EAU Guidelines Panel on Muscle-invasive and Metastatic Bladder Cancer)