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Treatment for male patients with primary urethral cancer

Treatment for primary urethral cancer in male patients depends on the cancer stage and location. Discover the options available and what to expect during therapy.

Understanding treatment options

Localised primary urethral cancer means the cancer is only in the urethra and hasn’t spread. Treatment is different in male and female patients. 

Your doctor will suggest a treatment that tries to remove all the cancer while helping you maintain a good quality of life. The location of the tumour plays a big role in choosing the right treatment.

This chapter contains general information about primary urethral cancer. It is not a substitute for professional medical advice or treatment. Always consult your doctor or healthcare provider for guidance on your individual medical situation.

Last updated: April 2026

Reviewed by (2026 update): 

  • Prof. Dr. Antoine Van Der Heijden (EAU Guidelines Panel on Muscle-invasive and Metastatic Bladder Cancer)
  • Prof. Dr. Yann Neuzillet (EAU Guidelines Panel on Muscle-invasive and Metastatic Bladder Cancer)