InPACT Trial
Researchers are trying to find out whether surgery to remove lymph nodes in the abdomen after chemotherapy or radiotherapy is better than surgery on its own. Or, whether a different operation to remove lymph nodes in the abdomen is better than standard surgery.
EPIC Trial
Researchers are trying to find out if immunotherapy treatment (see below) on its own or in combination with chemotherapy can reduce cancer that has spread to other parts of the body.
Immunotherapy
Immunotherapy is a treatment that uses your own immune system to fight tumour cells. It can cause cancer to shrink or sometimes disappear altogether.
Side Effects of Immunotherapy
Immunotherapy can cause mild, moderate, and even severe side effects. The most common include fatigue and flu-like symptoms, such as fever and chills, headaches, and pain in the muscles and joints. This is due to the body’s immune system becoming activate. Nearly everyone undergoing immunotherapy has these side effects at first. It usually gets better as treatment continues. Paracetamol can help to relieve these symptoms.
Immunotherapy can also have a temporary effect on blood cells in the body which may increase the risk of infection and make you feel tired or out of breath. Sometimes rashes may appear. Other symptoms include nausea and vomiting, diarrhoea, loss of appetite, and changes in taste or a metallic taste in your mouth. You could also experience a sore throat and pain when swallowing. Because these symptoms may lead to dehydration, weight loss, or malnutrition, be sure to let your doctor or nurse know if they do not go away.
During treatment, you may feel depressed, anxious, or have trouble sleeping. These feelings can be a side effect of immunotherapy, but they may also be a response to your diagnosis. You can ask your medical team about psychological support if you feel you need to have someone to talk to.
